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Who We Are

WESTERN
RESEARCH LAB

The research personnel from the Arts/Gao/Mann labs are located on the 2nd floor of the SDRI building but are moving to new state-of-the-art CL2+/CL3 facilities with Western HIV Investigator Group (WHIG) in 2016. The 6000 sqft ImPaKT biochemistry labs and the 4000 sqft ImPaKT CL2+/CL3 facilities will house projects on: HIV vaccine development, HIV virulence and evolution, HIV Cure, and drug resistance.

UGANDA
RESEARCH LAB

A core of 5 to 8 Ugandan scientists work in the CFAR Uganda molecular virology labs at the JCRC, directed by Dr. Immaculate Nankya. This lab was established by Dr. Arts in 1998 with the primary mission to understand HIV pathogenesis and to provide advanced clinical virology assays. As a WHO Regional Lab, the CFAR Uganda labs have performed over 5000 HIV-1 drug resistance tests for patients in East Africa.

CLINICAL
INNOVATION

With Dr. Miguel Quinones-Mateu we have been at the forefront of new vaccine approaches and new tests for HIV-1 clinical care. The lab has patented new cloning strategies for viruses, new multiplex methods for SNP detection, and new pipelines for Next Generation Sequencing. The Arts/Gao/Mann lab is also a participant of various international vaccine studies, EAVI2020 and collaborator of the first HIV vaccine trial in Canada.

INTERNATIONAL COLLABORATORS

Prof. Robin Shattock, Imperial College, UK and EAVI2020: HIV-1 transmission, vaccine, and CURE studies
Drs. Sarah Fidler and Caroline Foster, Imperial College and St. Mary’s Hospital, UK: HIV-1 CURE studies
Dr. Immaculate Nankya, Joint Clinical Research Centre, Uganda: HIV-1 pathogenesis and drug resistance
Dr. Miguel Quinones-Mateu, Case Western Reserve University (CWRU) and UHTL, USA: Assay development and drug resistance
Dr. Jeff Bailey, University of Massachusetts, USA: Bioinformatics and HIV-1 evolution
Dr. Chuanwu Zhu, The Fifth People’s Hospital of Suzhou, China: HIV-1 treatment outcomes and drug resistance
Dr. David McDonald, CWRU, USA: Restriction factors and HIV-1 pathogenesis
Dr. Robert Salata, CWRU, USA: HIV-1 clinical cohorts in Uganda
Dr. Jonathan Karn, CWRU, USA and Dr. Gabriele Varani, University of Washington, USA: HIV-1 RNA regulation and peptidomimetic inhibitors
Dr. James Mullins, University of Washington, USA: HIV-1 immune escape



Why Us?

The Arts/Gao/Mann Lab

     The Arts laboratory was founded in 1997 by Dr. Eric J. Arts at Case Western Reserve University in Cleveland, Ohio and then established a satellite laboratory at the Joint Clinical Research Centre in Kampala, Uganda. In 2014, we moved to Western University in London, Ontario from CWRU with strong research team and established a new home in the Department of Microbiology and Immunology at the Schulich School of Medicine and Dentistry. Over the past 20 years, we were honoured to have over 100 graduate students, post-doctoral fellows, clinical fellows, undergraduate students, visiting scientists and research assistants have worked with us on research projects related to HIV-1 pathogenesis, evolution, drug resistance, and molecular biology. Three faculty with strong collaborative ties and sharing common lab infrastructure.

     Arts/Gao/Mann Laboratory - committed to having fun, to developing new technologies, to being geeky scientists, and to finding a cure and vaccine for HIV-1

Meet the team behind our success.

Team HIV

Rick Gibson, BA, MSc
Rick Gibson, BA, MSc
Research Scientist. Interested in virus evolution and drug resistance using deep sequencing and leveraging these tools for clinical use.
Former contestant on American Idol.
Fernanda Russell
Fernanda Russell
Program Coordinator & Chair Assistant. Keeps the boss on track and on time.
Hula dancer from Hawaii.
Katie Bain
Katie Bain
Research Technician. Gets things done.
Colin Venner
Colin Venner
Graduate Student. Denison University 09. Immigrated from US to continue his work on the intersection between HIV evolution and pathogenesis.
#ballinoutofcontrol #labprincess
Seyed Moghadasi
Seyed Moghadasi, BMSc
Masters Student.
"Sexy and Snappy" - E. Arts
Josh Pankrac
Josh Pankrac, BMSc
Masters Student. Assisting Dr. Mann in the development of novel HIV vaccines.
Enjoys long walks on the beach.
Jason Knaap
Jason Knapp, BMSc
Masters Student. Working with Dr. Arts to increase the immunogenicity of a preventative VSV-based HIV vaccine.
Darshit Patel
Darshit Patel, BMSc
Masters Student
Chanuka Wijewardhana
Chanuka Wijewardhana, BMSc
Masters Student. Working with Dr. Mann on the development of therapeutic HIV vaccines.
Rahul Pawa
Rahul Pawa
4th year BMSc student.
Michael MacNeill
Michael MacNeill
4th year BMSc student.
Jenny Ma
Jenny Ma
4th Year MicroImm Honours Student. Working with Dr. Gao to explore production of endogenous anti-HIV broadly neutralizing antibodies.
#TagTeamDuo
Michelle Dong
Michelle Dong
4th year BMSc student. Working with Dr. Gao to study antigen-specific B cells for production of anti-HIV broadly neutralizing antibodies.
#TagTeamDuo